1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7190
    Yadanzioside F
    Inhibitor 98.0%
    Yadanzioside F is one of the toxic components found in Brucea javanica. Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties.
    Yadanzioside F
  • HY-W011239
    Fenbendazole sulfone
    Inhibitor
    Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent.
    Fenbendazole sulfone
  • HY-B0318S1
    Metronidazole-d4
    Inhibitor 98.25%
    Metronidazole-d4 is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
    Metronidazole-d<sub>4</sub>
  • HY-155732
    NPD-2975
    Inhibitor 98.40%
    NPD-2975 (compound 30) is an orally active antitrypanosomal agent, against Human African Trypanosomiasis (HAT). NPD-2975 has low toxicity potential against human MRC-5 lung fibroblasts, and acute mouse model of T. b. brucei infection. NPD-2975 shows acceptable metabolic stability, inhibits T. b. brucei with IC500 of 70 nM in vitro. NPD-2975 also inhibits CYP enzymes resulted in IC50 values of 0.16 and 0.42 μM against CYP1A2 and CYP2C19, respectively.
    NPD-2975
  • HY-B0744BR
    Eflornithine hydrochloride hydrate (Standard)
    Inhibitor
    Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine hydrochloride hydrate (Standard)
  • HY-119649S
    Flonicamid-15N18O
    98.0%
    Flonicamid-15N,18O (IKI220-15N,18O) is 15N labeled Flonicamid. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues.
    Flonicamid-<sup>15</sup>N<sup>18</sup>O
  • HY-N9488
    Girinimbine
    Inhibitor 99.23%
    Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities.
    Girinimbine
  • HY-17439R
    Salinomycin sodium salt (Standard)
    Salinomycin (sodium salt) (Standard) is the analytical standard of Salinomycin (sodium salt). This product is intended for research and analytical applications. Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt (Salinomycin sodium) shows selective activity against human cancer stem cells.
    Salinomycin sodium salt (Standard)
  • HY-N1480S
    (-)-Fucose-13C
    99.86%
    (-)-Fucose-13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti
    (-)-Fucose-<sup>13</sup>C
  • HY-105061
    Misonidazole
    98.74%
    Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer. Misonidazole also has antimicrobial effects.
    Misonidazole
  • HY-126741R
    Azadirachtin (Standard)
    Azadirachtin (Standard) is the analytical standard of Azadirachtin. This product is intended for research and analytical applications. Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin (Standard)
  • HY-17589S1
    Chloroquine-d4 phosphate
    Inhibitor 98.01%
    Chloroquine-d4 (phosphate) is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
    Chloroquine-d<sub>4</sub> phosphate
  • HY-N9991
    5-Hydroxy-3,7-dimethoxyflavone
    Control 99.89%
    5-Hydroxy-3,7-dimethoxyflavone (compound 1) can be isolated from Kaempferia parviflora, but has no significant toxicity to malaria parasites, fungi, and bacteria.
    5-Hydroxy-3,7-dimethoxyflavone
  • HY-N0110A
    Palmatine
    Inhibitor
    Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities.
    Palmatine
  • HY-N12788
    T-Cadinol
    Inhibitor 99.73%
    T-Cadinol is a sesquiterpene isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity, with IC50 values of 18.2 μM and 15.8 μM against trypomastigote and amastigote forms, respectively. T-Cadinol can induce mitochondrial damage in parasites, leading to membrane hyperpolarization and decreased levels of reactive oxygen species. T-Cadinol can be used for the research of Chagas disease.
    T-Cadinol
  • HY-B2138
    Ethopabate
    Inhibitor 99.22%
    Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Ethopabate
  • HY-115584R
    Lufenuron (Standard)
    Inhibitor
    Lufenuron (Standard) is the analytical standard of Lufenuron. This product is intended for research and analytical applications. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods.
    Lufenuron (Standard)
  • HY-130402B
    Propamidine
    Propamidine is a covalent inhibitor of TMPRSS2 and has some antibacterial activity..
    Propamidine
  • HY-W012192
    trans,trans-Dibenzylideneacetone
    Inhibitor 99.87%
    trans,trans-Dibenzylideneacetone ((E,E)-Dibenzylideneacetone) (compound A1) is a dibenzylideneacetone with a week antimalarial activity. trans,trans-Dibenzylideneacetone inhibits P. falciparum 3D7 strain with an IC50 of 213.41 μM.
    trans,trans-Dibenzylideneacetone
  • HY-N2906
    Limonianin
    Inhibitor
    Limonianin (Atalantoflavone) is a flavone, that can be isolated from Erythrina sigmoidea and the root bark of Citrus limonia. Limonianin presents inhibitory effect against P. gingivalis. Limonianin shows cytotoxic activity against multidrug-resistant (MDR) cancer cell lines.
    Limonianin

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